Abstract： Objective： To observe the clinical effect of Chinese medicine nursing on prevention of deep venous thrombosis of the lower limbs of senile patients after surgery of femoral neck fracture. Methods：A total of 103 cases of senile patients with femoral neck fracture were selected and divided into the control group and the observation group according to the random number table method，51 and 52 cases in each group respectively. The control group was given routine nursing， and the observation group was additionally given Chinese medicine nursing based on the treatment of the control group. Value of oxidative stress in serum， indexes of blood coagulation， blood flow velocity of femoral vein， pain score， whole blood viscosity，as well as swelling degree of the lower limbs and incidence of thrombus before and after nursing were compared in the two groups. Results： Before nursing， when compared mean blood flow velocity of femoral vein in affected limbs， scores of Visual Analogue Scale(VAS)，and whole blood viscosity between the two groups，there was no significance being found in the difference(P＞0.05). After nursing，mean blood flow velocity of femoral vein in affected limbs in the two groups was increased when compared with that before nursing，and the mean velocity in the observation group was higher than that in the control group(P＜0.05)；VAS scores and whole blood viscosity in the two groups were decreased when compared with those before nursing， and the two indexes in the observation group were lower than those in the control group(P＜0.05). After nursing，swelling degree of the lower limbs and incidence of thrombus in the observation group were significantly lower than those in the control group， the difference being significant(P＜0.05). Before nursing， when compared levels of superoxide dismutase(SOD) and malondialdehyde(MDA)，thrombin time(TT) and activated partial thromboplastin time(APTT) between the two groups，there was no significance being found in the difference(P＞0.05). After nursing，levels of SOD in the two groups were increased when compared with those before nursing，and TT and APTT were prolonged；level of SOD in the observation group was higher than that in the control group，and TT and APTT were longer than those in the control group(P＜0.05). After nursing，levels of MDA in the two groups were decreased when compared with those before nursing， and the level in the observation group was lower than that in the control group(P＜0.05). Conclusion：For senile patients with femoral neck fracture，Chinese medicine nursing can effectively improve stress response and indexes of blood coagulation after surgery， increase mean blood flow velocity of femoral vein， relieve pain in affected limbs and swelling degree， and reduce blood viscosity and incidence of thrombus.