Abstract： Objective： To observe the curative effect of external application of Chinese herbal cake with paraffin wax combined with retention enema with Qingre Huoxue enema liquid for chronic pelvic inflammation of dampness- heat accumulation type. Methods：A total of 60 cases of patients with chronic pelvic inflammation of dampness-heat accumulation type were divided into the control group and the observation group according to the random number table method，30 cases in each group. The control group was treated with retention enema with Qingre Huoxue enema liquid，and the observation group was additionally treated with external application of Chinese herbal cake with paraffin wax based on the treatment of the control group. Both groups were treated for three menstrual cycles. Chinese medicine syndrome scores， clinical effect， blood routine， and level of C- reactive protein(CRP) in serum were compared between the two groups. Results： After treatment，Chinese medicine syndrome scores in the two groups were decreased(P＜0.01)；the decrease in the observation group was more significant than that in the control group(P＜0.01). The total effective rate was 96.67% in the observation group， significantly higher than that of 73.33% in the control group(P＜0.05). After treatment， ratio of neutrophil and leukocyte as well as the serum CRP level were decreased in the two groups(P＜0.01)； the ratio and the level in the observation group were lower than those in the control group(P＜0.01). Conclusion： In the treatment of chronic pelvic inflammation of dampness- heat accumulation type， the therapy of external application of Chinese herbal cake with paraffin wax combined with retention enema with Qingre Huoxue enema liquid has significant curative effect and good anti-inflammatory effect，which can promote the improvement of Chinese medicine syndrome.