止咳方联合复方甲氧那明胶囊治疗感染后咳嗽临床研究
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R256.11

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Clinical Study on Zhike Prescription Combined with Compound Methoxyphenamine Capsules for Post-Infectious Cough
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    摘要:

    目的:观察中药止咳方联合复方甲氧那明胶囊治疗感染后咳嗽的临床效果。方法:将91 例感染后咳嗽患者,按随机数字表法将其分成2 组。对照组45 例患者采用复方甲氧那明胶囊治疗;观察组46 例患者采用复方甲氧那明胶囊联合中药止咳方治疗。对比2 组患者治疗前后日间咳嗽症状积分、夜间咳嗽症状积分、免疫球蛋白(Ig) 指标IgM、IgA、IgG 和C-反应蛋白(CRP) 水平变化情况。结果:观察组治疗4 d、8 d 及10 d 后日间咳嗽症状积分低于对照组,差异有统计学意义(P<0.05)。观察组治疗4 d、8 d 及10 d 后夜间咳嗽症状积分低于对照组,差异有统计学意义(P<0.05)。观察组治疗后免疫球蛋白指标IgM、IgA、IgG 与对照组相比明显升高,CRP 较治疗前及对照组均改善,差异有统计学意义(P<0.05)。结论:中药止咳方联合复方甲氧那明胶囊治疗感染后咳嗽,可显著减轻患者临床症状,有效抑制机体炎症水平,减轻气道反应,调节免疫功能。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Chinese medicine Zhike prescription combined with compound methoxyphenamine capsules for post-infectious cough. Methods:A total of 91 cases of patients with post-infectious cough were divided into the control group and the observation group according to the random number table method , 45 and 46 cases in each group respectively. The control group was treated with compound methoxyphenamine capsules,and the observation group was treated with compound methoxyphenamine capsules combined with Chinese medicine Zhike prescription. Before and after treatment, the changes in symptom scores of cough in the daytime and at night, levels of immunoglobulin(Ig) markers including IgM, IgA and IgG, and C- reactive protein(CRP) in the two groups were compared. Results: After treatment for four, eight and ten days respectively, the symptom score of cough in the daytime in the observation group were lower than those in the control group,the difference being significant(P<0.05). After treatment for four,eight and ten days respectively,the symptom score of cough at night in the observation group were lower than those in the control group,the difference being significant(P<0.05). After treatment,the levels of immunoglobulin markers including IgM,IgA and IgG in the observation group were significantly increased when compared with those in the control group,CRP was improved than before treatment and that in the control group, the difference being significant(P<0.05). Conclusion: Chinese medicine Zhike prescription combined with compound methoxyphenamine capsules for post- infectious cough can significantly relieve clinical symptoms,effectively inhibit the inflammatory levels of the body,relieve airway responsiveness and regulate immune function.

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顾大伟.止咳方联合复方甲氧那明胶囊治疗感染后咳嗽临床研究[J].新中医,2021,53(10):41-44

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  • 在线发布日期: 2021-05-24
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