Abstract：Objective：To observe the clinical effect of Yougui pills combined with point application for erectile dysfunction (ED) of kidney yang deficiency type. Methods： A total of 96 cases of patients were randomly divided into two groups ， 48 cases in each group. The treatment group was given oral administration of Yougui pills(granule formulations) combined with point application at Guanyuan point(CV 4) and Shenque point(CV 8)，and the control group was simply treated with Yougui pills (granule formulations). Both groups were treated for one course，one month being one course. Before and after treatment， the clinical effect and the scores of International Index of Erectile Function Questionnaire - 5(IIEF-5) in the two groups were recorded and compared. Results：After one- month treatment，the total effective rate was 85.42% in the treatment group and 72.92% in the control group， and there was significant difference being found in the comparison of the clinical effect between the two groups(P＜0.05). The IIEF- 5 scores in the two groups were increased when compared with those before treatment， differences being significant(P＜0.05)， and the improvement effect in the treatment group was significantly better than that in the control group，the difference being significant(P＜0.05). Conclusion：Yougui pills combined with point application has good effect in ED of kidney yang deficiency type.