Abstract：Objective：To observe the effect of Chinese medicine nursing on quality of life，unhealthy psychology and progesterone levels in patients with early threatened abortion. Methods：A total of 86 cases of patients with early threatened abortion were divided into the control group and the observation group according to the random number table method ， 43 cases in each group. The control group was given routine nursing，and the observation group was additionally treated with Chinese medicine nursing based on the treatment of the control group. The improvement of clinical symptoms，progesterone levels， quality of life， sleep quality and bad mood in the two groups was compared. Results： The stopping time of hemorrhage and the remission time of abdominal pain and low back pain in the observation group were significantly shorter than those in the control group(P＜0.05). After nursing， the levels of progesterone and β-human chorionic gonadotropin (β-HCG) in the two groups were increased when compared with those before nursing(P＜0.05)，and the above levels in the observation group were higher than those in the control group(P＜0.05). After nursing，the scores of energy，physiological function，social function，emotional function and mental health in the two groups were significantly higher than those before nursing(P＜0.05)，and the scores of all dimensions in quality of life in the observation group were higher than those in the control group(P＜0.05). After nursing，the scores of all dimensions of Pittsburgh Sleep Quality Index(PSQI) in the two groups were significantly lower than those before nursing(P＜0.05)；all dimensions of PSQI in the observation group were lower than those in the control group(P＜0.05). After nursing，the scores of Self- rating Anxiety Scale(SAS) and Self- rating Depression Scale(SDS) in the two groups were lower than those before nursing(P＜0.05)，and the above two scores in the observation group were lower than those in the control group(P＜0.05). Conclusion： Based on routine nursing， the intervention of Chinese medicine nursing for patients with early threatened abortion can attain good clinical effect， effectively eliminate clinical symptoms，relieve bad mood，improve sleep quality，significantly increase their progesterone levels，enhance the effect of calming the fetus and improve quality of life.