Abstract:Objective:To observe the effect of electroacupuncture for pain after cesarean section and its effect on levels of prostaglandin E2(PGE2) and β-endorphin(β-EP) in plasma. Methods:A total of 100 cases of puerpera undergoing cesarean section were divided into the control group and the observation group according to the random number table method , 50 cases in each group. The control group was given patient- controlled intravenous analgesia(PCIA) with sufentanil 30 minutes after surgery,and the observation group was additionally treated with electroacupuncture based on the treatment of the control group. Both groups were treated for two days. The levels of PGE2 and β-EP in plasma,the Visual Analogue Scale (VAS), the pressing times of PCIA, the analgesic quality and the incidence of adverse reactions in the two groups were compared. Results:After one-day treatment,the levels of PGE2 and β-EP in plasma and the VAS scores in the two groups were significantly increased when compared with those before treatment,and the above indexes in the observation group were lower than those in the control group(P<0.05). After two-day treatment,the levels of PGE2 and β-EP in plasma and the VAS scores in the two groups were lower than those after one-day treatment,and the above indexes in the observation group were lower than those in the control group(P<0.05). After treatment, the average pressing times of PCIA in the observation group were fewer than those in the control group(P<0.05). The excellent and good rate of analgesic was 100% in the observation group, higher than that of 92.00% in the control group, the difference being significant(P<0.05). The incidence of adverse reactions was 6.0% in the observation group and 14.00% in the control group, there being no significance in the difference(P>0.05). Conclusion:The electroacupuncture for pain after cesarean section can rapidly relieve pain of puerpera with good safety.