Abstract：Objective：To observe the clinical effect of the application of aromatherapy by massage along meridians for hyperplasia of mammary glands of the liver qi depression type. Methods：A total of 86 cases of patients with hyperplasia of mammary glands of the liver qi depression type who met the inclusion criteria were selected，and divided into two groups according the random number table method，43 cases in each group. The observation group was given aromatherapy by massage along meridians combined with Rupixiao granules，and the control group was given Rupixiao granules. Both groups were treated for three courses，four weeks being a course. The scores of Visual Analogue Scale(VAS)，Hamilton Anxiety Scale(HAMA)， and Hamilton Depression Scale(HAMD)， the size of breast mass， and the scores of Chinese medicine concomitant symptoms were recorded and compared between the two groups before and after treatment. Results：After treatment，the VAS scores of pain in the two groups were lower than those before treatment，and the sizes of breast mass were smaller：after treatment，the two indexes above in the observation group were lower than those in the control group， differences being significant(P＜0.05). After treatment， the scores of Chinese medicine concomitant symptoms， namely distention and fullness in the chest and hypochondrium，vexation and bitter taste in the mouth，inability to sleep and profuse dreaming，and liability to depression and anger，as well as the total score in the two groups were lower than those before treatment，differences being significant(P＜0.05). After treatment，the scores of vexation and bitter taste in the mouth，and liability to depression and anger as well as the total score in the observation group were lower than those in the control group， differences being significant(P＜0.05). After treatment，the scores of HAMA and HAMD in the two groups were lower than those before treatment，and the two scores above in the observation group were lower than those in the control group，the difference being significant(P＜0.05). The comparison of the clinical effect between the two groups showed significance in the difference(P＜0.05). The total effective rate was 90.7% in the observation group， and 69.8% in the control group， the difference being significant(P＜0.05). Conclusion： The application of aromatherapy by massage along meridians has good curative effect in the treatment of hyperplasia of mammary glands of the liver qi depression type，which can improve various degrees of anxiety and depression without significant adverse reactions.