Abstract： Chronic kidney disease has become a global public health security problem， and nocturia is one of the common clinical symptoms of chronic kidney disease. The pathophysiological mechanism of nocturia is complex and the etiology is diverse. Western medicine has its limitations in the treatment of nocturia. At present，Chinese medicine treatment has become a new trend in the treatment of various diseases. Chinese medicine internal treatment for chronic kidney disease with nocturia includes Xiayuxue tang，Guben Huayu tang，Suoquan capsules，compound Centella asiatica mixture，Liuwei Dihuang pills. The treatment methods include "Liudui Lunzhi"，Jianpi Yishen Danshen method，and so on，which are of great significance to relieve nocturia. The external treatment of Chinese medicine includes point massage， acupuncture， moxibustion， cupping， point application， herbal fumigation， colon dialysis with Chinese medicine， iontophoresis with Chinese medicine，and other methods，which can significantly relieve nocturia in chronic kidney disease.