复明胶囊联合玻璃酸钠滴眼液治疗白内障术后干眼症临床研究
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R779.66

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Clinical Study on Fuming Capsules Combined with Sodium Hyaluronate Eye Drops for Dry Eye After Cataract Surgery
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    摘要:

    目的:观察复明胶囊联合玻璃酸钠滴眼液治疗白内障术后干眼症的临床疗效。方法:纳入因白内障手术后出现干眼症的患者94 例,按随机数字表法分为对照组与观察组,每组47 例。对照组给予玻璃酸钠滴眼液治疗,观察组在对照组治疗的基础上加用复明胶囊口服。比较治疗前后2 组干眼临床表现评分、泪液分泌试验(Schirmer I)、泪膜破裂时间(BUT)、角膜荧光素染色(FL) 情况,并统计2 组总体临床疗效。结果:愈显率观察组为95.74%,对照组为72.34%,2 组比较,差异有统计学意义(P<0.05)。治疗后,2 组干眼症状评分均较治疗前明显降低(P<0.05),且观察组干眼症状评分低于对照组(P<0.05)。治疗后,2 组患者Schirmer I、BUT 值均较治疗前升高(P<0.05),FL 评分较治疗前降低(P<0.05);且观察组各项指标改善较对照组更显著(P<0.05)。结论:复明胶囊联合玻璃酸钠滴眼液治疗白内障术后干眼症,可增加泪液分泌,更好地稳定泪膜,缓解干眼症状,疗效优于单纯玻璃酸钠滴眼液治疗。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Fuming capsules combined with sodium hyaluronate eye drops for dry eye after cataract surgery. Methods:A total of 94 cases of patients with dry eye after cataract surgery were selected and divided into the control group and the observation group according to the random number table method, 47 cases in each group. The control group was treated with sodium hyaluronate eye drops,and the observation group was additionally given oral administration of Fuming capsules. Before and after treatment,the scores of clinical manifestation of dry eye,Schirmer I test, tear break- up time(BUT), and cornea fluorescein staining(FL) were compared between the two groups. The total clinical effect was counted in the two groups. Results:The cure and markedly effective rate was 95.47% in the observation group,and 72.34% in the control group,the difference being significant(P<0.05). After treatment,the symptom scores of dry eyein the two groups were significantly decreased when compared with those before treatment(P<0.05),and the score in the observation group was lower than that in the control group(P<0.05). After treatment,the scores of Schirmer I test and BUT in the two groups were increased when compared with those before treatment(P<0.05), and the scores of FL were decreased(P<0.05); the improvement of each index above in the observation group was more significant than that in the control group(P<0.05). Conclusion:For dry eye after cataract surgery,the therapy of oral administration of Fuming capsules combined with sodium hyaluronate eye drops can promote tear secretion, better stabilize tear film, and alleviate dry eye symptoms. Its curative effect is better than that of simple sodium hyaluronate eye drops.

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沙恒,懒晓明,王盛盏.复明胶囊联合玻璃酸钠滴眼液治疗白内障术后干眼症临床研究[J].新中医,2020,52(21):72-74

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  • 在线发布日期: 2020-11-05
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