润肠通便汤联合推拿治疗儿童功能性便秘临床研究
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R244.1;R256.35

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郑州大学人民医院23456人才工程基金项目(ZC234561242)


Clinical Study on Runchang Tongbian Tang Combined with Tuina for Functional Constipation in Children
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    摘要:

    目的:观察润肠通便汤加减联合推拿治疗功能性便秘患儿的临床疗效。方法:选择功能性便秘患儿100 例,按随机数字表法分为对照组和观察组各50 例。对照组给予润肠通便汤加减治疗,观察组在对照组的基础上联合推拿治疗,均治疗3周。观察2 组临床疗效,比较主症与症状总积分、肛门直肠动力学指标、胃肠激素水平的变化,评价2 组治疗安全性。结果:观察组总有效率为92.00%,高于对照组74.00%,差异有统计学意义(P<0.05)。治疗后,2 组主症积分、症状总积分较治疗前明显降低(P<0.05),且观察组主症积分、症状总积分低于对照组(P<0.05)。治疗后,2 组直肠最低敏感量、直肠最大耐受量、肛门括约肌最大收缩压较治疗前明显降低(P<0.05),且观察组直肠最低敏感量、直肠最大耐受量、肛门括约肌最大收缩压均低于对照组(P<0.05)。治疗后,2 组胃动素、胃泌素、胃肠激素P 物质水平较治疗前升高,且观察组胃动素、胃泌素、胃肠激素P 物质水平高于对照组(P<0.05);2 组生长抑素水平较治疗前降低,且观察组生长抑素水平低于对照组(P<0.05)。2 组患儿治疗期间无明显不良反应发生。结论:润肠通便汤联合推拿治疗功能性便秘患儿疗效显著。

    Abstract:

    Abstract:Objective:To observe the clinical effect of modified Runchang Tongbian tang combined with tuina for children with functional constipation. Methods:A total of 100 cases of children with functional constipation were selected and divided into the control group and the observation group according to the random number table method,50 cases in each group. The control group was treated with modified Runchang Tongbian tang,and the observation group was additionally treated with tuina based on the treatment of the control group. Both groups were treated for three weeks. The clinical effect in the two groups was observed;the changes of the scores of main symptoms and the total scores of symptoms,indexes of anorectal motility and levels of gastrointestinal hormones were compared;the safety of treatment in the two groups was evaluated. Results:The total effective rate was 92.00% in the observation group,higher than that of 74.00% in the control group,the difference being significant(P<0.05). After treatment,the scores of main symptoms and the total scores of symptoms in the two groups were significantly decreased when compared with those before treatment(P<0.05), and the scores in the observation group were lower than those in the control group(P<0.05). After treatment,the rectal lowest volume of sensory threshold, the rectal maximum tolerance, and the maximal systolic pressure of anal sphincter in the two groups were significantly decreased when compared with those before treatment(P<0.05), and the above indexes in the observation group were all lower than those in the control group(P<0.05). After treatment, the levels of motilin, gastrin and gastrointestinal hormone P in the two groups were increased when compared with those before treatment,and the levels in the observation group were higher than those in the control group(P<0.05); the levels of somatostatin in the two groups were decreased when compared with those before treatment,and the level in the observation group was lower than that in the control group(P<0.05). During the treatment,no obvious adverse reaction occurred in the two groups. Conclusion:The therapy of Runchang Tongbian tang combined with tuina has significant curative effect in treating functional constipation in Children.

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王冬梅,王美娟.润肠通便汤联合推拿治疗儿童功能性便秘临床研究[J].新中医,2020,52(21):68-71

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  • 在线发布日期: 2020-11-05
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