Abstract： Objective： To observe the curative effect of point application of modified Liumo tang at Shenque(CV8) combined with Simo tang oral liquid for constipation induced by antipsychotic medicine. Methods： A total of 110 cases of patients with constipation due to qi stagnation were randomly divided into two groups，55 cases in each group. Both groups were given Simo tang oral liquid， adjustment of their life style， abdominal massage and other nursing measures. The observation group was additionally treated with point application of modified Liumo tang at Shenque(CV8) based on the treatment of the control group. Both groups were treated for four weeks， five days being a course. Before and after treatment， the scores of main symptoms of constipation and Patient Assessment of Constipation Symptoms(PAC- SYM) were evaluated. The average times of spontaneous complete bowel movement(SCBM) per week were recorded one week before treatment and seven days after four weeks of treatment. The clinical effect in the two groups was compared. Results： After treatment，the clinical effect in the observation group was better than that in the control group(P＜0.05). The scores of abdominal symptoms， rectal symptoms， stool symptoms and the total scores of PAC- SYM in the two groups were decreased when compared with those before treatment(P＜0.01)，and the above scores in the observation group were lower than those in the control group(P＜0.01). The scores of main symptoms of constipation in the two groups were decreased when compared with those before treatment(P＜0.01)，and the time of SCBM were increased when compared with those before treatment(P＜0.01). The scores of main symptoms of constipation in the observation group were lower than those in the control group(P＜0.01)，and the time of SCBM was more than that in the control group(P＜0.01). Conclusion：Based on Simo tang oral liquid and routine nursing measures，the intervention of point application of modified Liumo tang at Shenque (CV8) on constipation induced by antipsychotic medicine can effectively improve constipation- related symptoms and clinical effect.