Abstract： Objective： To observe the clinical effect of Kegan Liyan oral lipid in adjuvant therapy of acute suppurative tonsillitis with the syndrome of wind-heat and pathogenic toxin invading the lung in children. Methods：A total of 150 cases of children were randomly divided into the observation group and the control group， 75 cases in each group. In the control group， the oral administration of cefaclor for suspension was for children with mild symptoms， the intravenous drip of azithromycin for injection for those with severe symptoms， and the oral administration of ibuprofen suspension for those whose body temperature was at 38.5 ℃ or above. The observation group was additionally given oral administration of Kegan Liyan oral lipid based on the treatment of the control group. The scores of Visual Analogue Scale(VAS) and the syndrome of wind- heat and pathogenic toxin invading the lung， the time for temperature back to normal， the regression time of pharyngeal hyperemia and the disappearance time of purulent secretion were observed and compared between the two groups. The changes in the levels of white blood cell(WBC) count，neutrophil(N) and C-reactive protein(CRP) before and after treatment were detected in the two groups. Results：The total effective rate was 100% in the observation group and 96.00% in the control group；the difference being significant(P＜0.05)，and the curative effect in the observation group was better than that in the control group. The fever subsidence time，the disappearance time of purulent secretion and the regression time of pharyngeal hyperemia in the observation group were significantly shorter than those in the control group， the difference being significant(P＜0.05). On the 3rd，5th，7th and 10th days after treatment，the VAS scores of sore throat in the two groups were significantly decreased when compared with those before treatment(P＜0.05)；the scores at different time points in the observation group were lower than those in the control group(P＜0.05). After treatment，the values of WBC，N and CRP in the two groups were significantly decreased when compared with those before treatment(P＜0.05)；the above three indexes in the observation group were significantly lower than those in the control group(P＜0.05). Conclusion： In adjuvant therapy for children with acute suppurative tonsillitis with the syndrome of wind-heat and pathogenic toxin invading the lung， Kegan Liyan oral lipid can significantly alleviate sore throat， shorten the course of the disease and relieve inflammatory responses with significant clinical effect.