Abstract： Objective： To investigate the curative effect and safety of Diankuang Mengxing tang combined with aripiprazole oral disintegrating tablets for male patients with schizophrenia of qi stagnation and blood stasis type. Methods：A total of 76 cases of male patients with schizophrenia hospitalized in the psychiatric department of Tongde Hospital of Zhejiang Province from October 2017 to January 2019 were divided into the study group and the control group according to the method of random sampling，38 cases in each group. The control group was given oral administration of aripiprazole，and the study group was additionally treated with modified Diankuang Mengxing tang based on the treatment of the control group. Both groups were treated for eight weeks. The curative effect as well as adverse reactions after treatment in the two groups were compared. Results：After eight weeks of treatment，the total effective rate was 91.4% in the study group ，higher than that of 71.9% in the control group(P＜0.05)；the total score of Positive and Negative Symptom Scale(PANSS) in the study group was significantly lower than that in the control group(P＜0.05)；the incidence of adverse reactions in the two groups showed no significance in the difference. Conclusion： The therapy of Diankuang Mengxing tang combined with aripiprazole oral disintegrating tablets has good curative effect and safety in treating schizophrenia，which is a new choice of treatment.