Abstract: Objective: To summarize and organize processing methods of mineral medicine in Leigong Paozhi Lun, in order to contribute to inheriting and innovating traditional processing methods of Chinese herbs. Methods: Based on the master copy for research of Leigong Paozhi Lun supplemented by ZHANG Ji and checked and annotated by SHI Zhong'an in Qing Dynasty, processing methods and their functions of 20 kinds of mineral medicines recorded in the book were briefly summarized and discussed through reading,analysis and the inquiry of reference documents. Results:Processing methods of mineral medicine recorded in Leigong Paozhi Lun can be summarized in five categories:cleaning method,water- grind method,dry-heat method,water-boiling method and reproduction method. During processing of medicines,there were 2 kinds of mineral medicines processed by cleaning method ,6 kinds by water-grind method,5 kinds by dry-heat method, 16 kinds by water-boiling method and 6 kinds by reproduction method. Conclusion:Processing methods of mineral medicine recorded in Leigong Paozhi Lun are more complicated, some of which and technologies are still employed by later generations. The methods in the book can provide certain ideas and references for promotion of processing theories and technologies in later modern research of Chinese herbs.