Abstract： Objective： To observe the clinical effect of the method of Chinese medicine regulating menstruation for patients with polycystic ovary syndrome(PCOS) of kidney deficiency type at child- bearing period. Methods： A total of 94 patients with PCOS of kidney deficiency type at child-bearing period were selected and divided into the control group and the observation group according to the random number table，47 cases in each group. The control group was treated with oral clomiphene citrate and intramuscular injection of human chorionic gonadotropin. The observation group was additionally treated with the method of Chinese medicine regulating menstruation based on the treatment of the control group. Both groups were treated for three menstrual cycles. The therapeutic effect，Chinese medicine syndrome score，ovarian volume，endometrial thickness and level of sex hormone before and after treatment were compared between the two groups. Results：The total effective rate was 85.11% in the observation group，higher than that of 65.96% in the control group(χ 2= 4.663，P=0.027＜0.05). After treatment，the scores of menstrual disorders，mental fatigue and weakness，soreness and weakness of waist and knees，tinnitus or deafness，and loss of libido in the two groups were all decreased when compared with those before treatment(P＜0.05)，and the above five scores of Chinese syndrome in the observation group were lower than those in the control group(P＜0.05). There was no significant differences in the comparison of endometrial thickness and ovarian volume in the control group before and after treatment(P＞0.05). The endometrial thickness in the observation group was increased when compared with that before treatment(P＜0.05)，and the ovarian volume was decreased(P＜0.05)；the endometrial thickness in the observation group was larger than that in the control group(P＜0.05)， and the ovarian volume was smaller than that in the control group(P＜0.05). There was no significant differences in the comparison of the levels of luteinizing hormone(LH)，follicle stimulating hormone(FSH)，LH/FSH and testosterone(T) in the control group before and after treatment(P＞0.05). The T level in the observation group was decreased when compared with that before treatment(P＜0.05) and lower than that in the control group(P＜0.05). Conclusion：The method of Chinese medicine regulating menstruation has significant therapeutic effect in treating patients with PCOS of kidney deficiency type at child- bearing period， which can effectively improve the clinical symptoms， increase endometrial thickness， reduce ovarian volume and reduce T level in serum.