Abstract：Prof. ZHANG Bei puts forward that the pathogenesis of tumor is mostly related to phlegm，toxin，stasis and deficiency， and that the clinical treatment of it should be placed value on the “holistic concept and syndrome differentiation”， the essence of the diagnosis and treatment of Chinese medicine. She also believes that the disease differentiation and syndrome differentiation should be combined organically， and emphasis should be on reinforcing healthy qi and securing the root， securing and strengthening the spleen and stomach. It is pointed out that "treating the root of disease" is the main method to guide the treatment of tumor. In addition， she proposes the application of "counteracting toxin with toxin" in treating tumor， and first puts forward that whether the blue-purple tongue disappears or not，and whether it disappears sooner or later， can be regarded as one of the prognostic indicators. Last but not least， she attaches great importance to “treating disease before it arises”， and advocates the comprehensive application of Chinese medicine and western medicine including surgery， radiotherapy，chemotherapy， interventional therapy and targeted therapy，so as to form a theoretical system of comprehensive treatment with the characteristics of Chinese medicine.