穿王消炎胶囊联合开喉剑喷雾剂治疗慢性咽喉炎临床研究
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R766.5

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Clinical Study on Chuanwang Xiaoyan Capsules Combined with Kaihoujian Spray for Chronic Laryngopharyngitis
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    摘要:

    目的:观察穿王消炎胶囊联合开喉剑喷雾剂治疗慢性咽喉炎的临床疗效。方法:选取290例慢性咽喉炎患者,按随机数字表法分为A组与B组,每组145例。A组予以开喉剑喷雾剂治疗,B组予以穿王消炎胶囊联合开喉剑喷雾剂治疗,持续治疗10 d。对比2 组临床疗效、临床症状改善时间及治疗前后炎症因子水平的变化。结果:B 组总有效率为93.8%,高于A 组的74.5%,差异有统计学意义(P<0.05)。B 组咽喉痛痒、咽喉异物感、干咳改善时间均短于A 组,差异均有统计学意义(P<0.05)。治疗后,2组C-反应蛋白(CRP)、白细胞介素-4(IL-4)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α) 水平均较治疗前降低(P<0.05),B组上述4项炎症因子水平均低于A组(P<0.05)。结论:穿王消炎胶囊联合开喉剑喷雾剂治疗慢性咽喉炎效果显著,可快速改善患者的临床症状,降低炎症因子水平。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Chuanwang Xiaoyan capsules combined with Kaihoujian spray for chronic laryngopharyngitis. Methods:A total of 290 cases of patients with chronic laryngopharyngitis were divided into Group A and Group B according to the random number table method,145 cases in each group respectively. Group A was treated with Kaihoujian spray,and Group B was additionally treated with Chuanwang Xiaoyan capsules. Both groups were treated for 10 days. The clinical effect,the improvement time of clinical symptoms as well as the changes in the levels of inflammatory factors before and after treatment were compared between the two groups. Results:The total effective rate was 93.8% in Group B,higher than that of 74.5% in Group A,the difference being significant(P<0.05). The improvement time of pain and itching in throat,foreign body sensation in throat,and dry cough in Group B was shorter than that in Group A,differences being significant(P<0.05). After treatment,the levels of C-reactive protein(CRP),interleukin-4(IL-4),interleukin-6(IL-6) and tumor necrosis factor- α(TNF- α) in the two groups were decreased when compared with those before treatment(P<0.05), and the above four levels in Group B were all lower than those in Group A(P<0.05). Conclusion: The therapy of Chuanwang Xiaoyan capsules combined with Kaihoujian spray has significant curative effect in treating chronic laryngopharyngitis,which can rapidly relive clinical symptoms,reduced the levels of inflammatory factors.

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朱迎虹,苏立众.穿王消炎胶囊联合开喉剑喷雾剂治疗慢性咽喉炎临床研究[J].新中医,2020,52(11):78-80

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  • 在线发布日期: 2020-06-04
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