加味活络效灵丹外敷联合综合护理辅助治疗肝癌癌性疼痛临床研究
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R735.7;R248

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Clinical Study on External Application of Modified Huoluo Xiaoling Pills Combined with Comprehensive Nursing in Adjuvant Therapy of Cancer Pain of Liver Cancer
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    摘要:

    目的:观察加味活络效灵丹外敷联合综合护理辅助治疗肝癌癌性疼痛的临床疗效。方法:将100 例中、重度肝癌癌性疼痛患者随机分为对照组50 例和观察组50 例。2 组患者均给予综合护理措施,对照组采用疼痛分阶梯治疗方案,给予氨酚曲马多片或硫酸吗啡缓释片治疗,每天进行疼痛程度评估并调整给药剂量;观察组在对照组的基础上加用加味活络效灵丹外敷,2 组疗程均为10 d。观察比较2 组治疗前、治疗后3 d、5 d、7 d、10 d 的疼痛视觉模拟评分法(VAS) 评分;观察比较2 组治疗前后面部表情疼痛评级,疼痛对情绪、睡眠、活动能力和食欲的影响;观察比较2 组治疗前后生活质量评分变化。结果:经秩和检验,治疗后观察组疼痛缓解优于对照组,差异有统计学意义(P<0.05)。治疗后3 d、5 d、7 d、10 d,2 组患者疼痛VAS 评分均较治疗前降低(P<0.05);且观察组在治疗后5 d、7 d 、10 d 的疼痛VAS 评分明显低于对照组(P<0.05)。经秩和检验,治疗后2 组患者面部表情疼痛情况均较治疗前显著改善(P<0.05);且观察组患者面部表情疼痛改善较对照组更显著(P<0.05)。治疗后2 组患者疼痛对情绪、睡眠、活动能力和食欲的影响评分均治疗前明显下降(P<0.05),且观察组各项评分均低于对照组(P<0.05)。治疗后,2 组患者生活质量评分均较治疗前明显降低(P<0.05),且观察组生活质量评分低于对照组(P<0.05)。 结论:综合护理联合加味活络效灵丹外敷辅助治疗肝癌癌性疼痛,可有效减轻疼痛症状,缓解疼痛带来的不良影响,从而提高患者的生活质量。

    Abstract:

    Abstract:Objective:To observe the clinical effect of external application of modified Huoluo Xiaoling pills combined with comprehensive nursing in adjuvant therapy of cancer pain of the liver cancer. Methods:A total of 100 cases of patients with moderate and severe cancer pain of the liver cancer were randomly divided into the control group and the observation group, 50 cases in each group. Both groups were given comprehensive nursing management measures. Based on the scheme of pain ladder treatment,the control group was additionally given paracetamol and tramadol hydrochloride tablets or morphine sulphate sustained- release tablets; the evaluation of pain degree was conducted every day, and medication dose was regulated; the observation group was additionally given external application of modified Huoluo Xiaoling pills based on the treatment of the control group. Both groups were treated for ten days. Before treatment as well as on the 3rd,5th,7th,and 10th days after treatment,the scores of Visual Analogue Scale(VAS) were observed and compared between the two groups. Before and after treatment,faces pain rating,and the effect of pain on emotions,sleep,activity ability,and appetite were observed and compared between the two groups. Before and after treatment,the changes in scores of quality of life were observed and compared between the two groups. Results:After treatment,pain relief in the observation group was better than that in the control group,the difference being significant(P<0.05). On the 3rd,5th,7th,and 10th days after treatment, the VAS scores in the two groups were decreased when compared with those before treatment(P<0.05);the scores in the observation group were significantly lower than those in the control group(P<0.05). After treatment,faces pain rating in the two groups was significantly improved when compared with that before treatment(P<0.05); the improvement in the observation group was more significant than that in the control group(P<0.05). After treatment,scores of the effect of pain on emotions,sleep,activity ability,and appetite in the two groups were significantly decreased when compared with those before treatment(P<0.05); each score in the observation group was lower than that in the control group(P<0.05). After treatment, scores of quality of life in the two groups were significantly decreased when compared with those before treatment(P<0.05); the score in the observation group was significantly lower than that in the control group(P<0.05). Conclusion:The therapy of comprehensive nursing combined with modified Huoluo Xiaoling pills in adjuvant therapy of cancer pain of the liver cancer, can effectively alleviate pain and harmful effect caused by pain, thus improving quality of life of patients.

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史建文,虞冻沨,潘松旦.加味活络效灵丹外敷联合综合护理辅助治疗肝癌癌性疼痛临床研究[J].新中医,2020,52(19):170-173

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  • 在线发布日期: 2020-10-12
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