Abstract： This paper introduces the academic thoughts and administration experiment of Professor XU Zhenye in the diagnosis and treatment of lung cancer. According to Professor XU zhenye，the lesions of lung cancer lie in the lung but do not limit to the lung. Essential qi deficiency is an important internal pathogen，involving the deficiency and damage of the lung，the spleen and the kidney. The main manifestations of the cancer focus in the lung are the binding of toxin， stasis and phlegm. Reinforcing the healthy qi is highlighted in the treatment principle of cancer. In clinic，doctors should value inquiry and tongue diagnosis， and treat the lung cancer by stages. In terms of the administration experiment， this paper conducts a comprehensive analysis from four perspectives including characteristic administration as well as the administration for main symptoms，for complications，and for deteriorated cases.