Abstract: Objective: To summary the clinical experience and administration rules of Professor Wang Bangcai in the treatment of chronic diarrhea,and to provide thinking and reference for the scientific research and clinical practice of Chinese medicine treatment of disease. Methods: The prescriptions of 200 patients with chronic diarrhea were collected. These patients,in accordance with the diagnostic criteria of chronic diarrhea,were treated by Professor WANG in Ningbo Hospital of Traditional Chinese Medicine from November, 2015 to December, 2017. The prescriptions were used for data mining through Chinese Medicine Inheritance Support System(V2.5). The administration rules of Professor WANG in treating chronic diarrhea were analyzed and studied by the statistics of frequency method, the improved mutual information method,complex system entropy cluster and unsupervised hierarchical cluster, etc. Results: A total of 200 prescriptions and 112 kinds of Chinese herbs were enrolled. The commonly- used herbs in treating chronic diarrhea included Radix Aucklandiae,Semen Lablab Album, Rhizoma Coptidis, stir- bake Rhizoma Atractylodis Macrocephalae and Rhizoma Zingiberis, which mainly involved deficiency-tonifying medicine,heat-clearing medicine,dampness-resolving medicine,exterior-releasing medicine and astringent medicine. The main property of Chinese herbs was warmth,and the major flavor was sweetness.The spleen meridian ranked first in meridian tropism. There were 39 high-frequency medicine combinations and 9 association rules according to the analysis of association rules,20 core medicine combinations based on the analysis of complex system entropy cluster, and 10 new prescriptions based on the analysis of unsupervised hierarchical cluster. Conclusion: In the treatment of chronic diarrhea,Professor Wang mainly used Chinese herbs which have the flavor of sweetness,the nature of warmth, and tropism of the spleen meridian and the stomach meridian. It shows the qi- blood regulation method, both warming and clearing method,both tonifying and discharging method,and calming mind by heavy settling method.