Abstract：Objective：To observe the nursing effect of emotion nursing of Chinese medicine on patients with depression after stroke. Methods：A total of 116 cases of patients with depression after stroke were divided into the observation group and the control group according to the random number table method，58 cases in each group. The control group was given routine nursing，and the observation group was given emotion nursing of Chinese medicine. Before and after treatment，the scores of Hamilton Depression Scale(HAMD)， Barthel index(BI) and Stroke Impact Scale(SIS) in the two groups were compared. The nursing satisfaction and curative effect were recorded. Results：The total effective rate was 94.83% in the observation group， higher than that of 79.31% in the control group， the difference being significant(P＜0.05). Before nursing，compared the scores of HAMD，BI and SIS in the two groups，there was no significance in the difference(P＞0.05). After nursing，the HAMD scores in the two groups were decreased when compared with those before treatment，and the scores of BI and SIS were increased，differences being significant(P＜0.05)；the HAMD score in the observation group was lower than that in the control group，and the scores of BI and SIS were higher，differences being significant(P＜0.05). The satisfaction rate was 96.55% in the observation group，higher than that of 82.76% in the control group，the difference being significant(P＜0.05). Conclusion：The application of emotion nursing of Chinese medicine for patients with depression after stroke can significantly relieve depression and improve curative effect， nursing satisfaction and quality of life， with high clinical value.