活血消瘿片合夏枯草胶囊治疗桥本氏甲状腺炎伴结节临床研究
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Clinical Study on Huoxue Xiaoying Pills Combined with Xiakucao Capsules for Hashi⁃moto's Thyroiditis Complicated with Nodules
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    摘要:

    目的:观察活血消瘿片合夏枯草胶囊治疗桥本氏甲状腺炎伴结节的临床疗效。方法:选择桥本氏甲状腺炎伴结节患者82例,按随机数字表法分为对照组和观察组各41例。对照组给予左甲状腺素钠片治疗,观察组给予活血消瘿片合夏枯草胶囊治疗。比较2 组临床疗效,治疗前后甲状腺结节直径、甲状腺功能和甲状腺抗体水平变化。结果:观察组总有效率为92.68%,高于对照组65.85%(P<0.05)。治疗前,2组甲状腺结节直径比较,差异无统计学意义(P>0.05)。治疗后,2组甲状腺结节直径较治疗前降低,且观察组甲状腺结节直径低于对照组,差异均有统计学意义(P<0.05)。治疗前,2组游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4) 和促甲状腺激素(TSH) 水平比较,差异无统计学意义(P>0.05)。治疗后,2组FT3、FT4和TSH水平较治疗前无明显变化(P>0.05),2组FT3、FT4和TSH水平比较,差异无统计学意义(P>0.05)。治疗前,2组抗甲状腺过氧化物酶抗体(TPOAb) 和抗甲状腺球蛋白抗体(TGAb) 水平比较,差异无统计学意义(P>0.05)。治疗后,2 组TPOAb 和TGAb水平较治疗前降低,观察组TPOAb和TGAb水平低于对照组,差异均有统计学意义(P<0.05)。结论:活血消瘿片合夏枯草胶囊对桥本氏甲状腺炎伴结节患者甲状腺功能无明显影响,可降低TPOAb和TGAb水平,疗效较好。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Huoxue Xiaoying pills combined with Xiakucao capsules for Hashimoto’ s thyroiditis complicated with nodules. Methods: A total of 82 cases of patients with Hashimoto's thyroiditis complicated with nodules were divided into the control group and the observation group according the random number table method, 41 cases in each group. The control group was treated with levothyroxine sodium tablets, and the observation group was treated with Huoxue Xiaoying pills combined with Xiakucao capsules. The clinical effect and the changes in the diameters of thyroid nodules, the thyroid function and the levels of thyroid antibody before and after treatment in the two groups were compared. Results:The total effective rate was 92.68% in the observation group,higher than that of 65.85% in the control group(P<0.05). Before treatment, there was no significant difference being found in the comparison of the diameters of thyroid nodules between the two groups(P>0.05). After treatment,the diameters of thyroid nodules in the two groups were decreased when compared with those before treatment, and the diameters in the observation group were smaller than those in the control group,differences being significant(P<0.05). Before treatment,compared the levels of free triiodothyronine(FT3), free thyroxine(FT4) and thyroid- stimulating hormone(TSH) between the two groups, there was no significance in the difference(P>0.05). Compared the levels of FT3,FT4 and TSH before and after treatment,there was no significant difference being found in either groups(P>0.05);no significant difference was found in the comparison between the two groups after treatment(P>0.05). Before treatment,compared the levels of thyroid peroxidase antibodies(TPOAb) and thyroglobulin antibodies(TGAb) between the two groups, there was no significance in the difference(P>0.05). After treatment,the levels of TPOAb and TGAb in the two groups were decreased when compared with those before treatment,and the levels in the observation group were lower than those in the control group, differences being significant(P<0.05).Conclusion: The therapy of Huoxue Xiaoying pills combined with Xiakucao capsules has no obvious effect on the thyroid function in patients with Hashimoto's thyroiditis complicated with nodules,and it can reduce the levels of TPOAb and TGAb,with good curative effect.

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黄国政,雷梅花,李平.活血消瘿片合夏枯草胶囊治疗桥本氏甲状腺炎伴结节临床研究[J].新中医,2020,52(10):53-56

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  • 在线发布日期: 2020-05-26
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