独活寄生汤联合经皮椎体成形术治疗老年女性骨质疏松性椎体压缩骨折临床研究
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Clinical Study on Duhuo Jisheng Tang Combined with Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fracture in Elderly Women
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    摘要:

    目的:观察独活寄生汤联合经皮椎体成形术(PVP) 治疗老年女性骨质疏松性椎体压缩骨折(OVCF) 的临床效果。方法:选取270例老年女性OVCF患者,按照随机数字表法分为A组、B组、C组,每组90例。A组采用PVP联合独活寄生汤治疗,B 组采用PVP 治疗,C 组采取保守治疗联合独活寄生汤。比较3 组视觉模拟评分法(Visual Analogue Scale,VAS) 评分、Oswestry 功能障碍指数(Oswestry Disability Index,ODI)、生化指标及骨密度。结果:术后1、3、6个月,3组VAS评分、ODI评分与治疗前比较,差异均有统计学意义(P<0.05);A 组VAS 评分、ODI 评分均低于B 组、C 组,差异有统计学意义(P<0.05)。术后3个月,3组股骨近端骨密度、生化指标均较治疗前改善,差异有统计学意义(P<0.05);A组股骨近端骨密度高于B组、C组(P<0.05),A组生化指标较B组、C组改善程度更多(P<0.05)。结论:独活寄生汤联合PVP治疗OVCF,可以有效缓解患者疼痛,改善下肢功能,减缓骨质疏松症进展。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Duhuo Jisheng tang combined with percutaneous vertebroplasty(PVP) for osteoporotic vertebral compression fracture (OVCF) in elderly women. Methods: A total of 270 elderly female patients with OVCF were selected and divided into Group A,Group B and Group C according to the random number table method,90 cases in each group. Group A was treated with PVP combined with Duhuo Jisheng tang;Group B was treated with PVP, and Group C was treated with conservative treatment combined with Duhuo Jisheng tang. The score of Visual Analogue Scale(VAS),score of Oswestry Disability Index(ODI),biochemical indexes and bone mineral density were observed and compared between the three groups. Results: After the first, third and sixth months of postoperation, there were significant differences in the comparison of the scores of VAS and ODI between the three groups(P<0.05),and the scores of VAS and ODI in Group A were lower than those in Group B and Group C,the difference being significant(P<0.05). After the third month of postoperation,the bone mineral density,and biochemical indexes in the three groups were improved when compared with those before treatment,the difference being significant(P<0.05);the bone mineral density in Group A was higher than that in Group B and Group C respectively(P<0.05),and the biochemical indexes in Group A were improved better than those in Group B and Group C respectively(P<0.05). Conclusion: The therapy of Duhuo Jisheng tang combined with PVP for patients with OVCF,which can effectively relieve pain,improve lower limb function and slow down the progression of osteoporosis.

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张东明,屠震宇,施金江.独活寄生汤联合经皮椎体成形术治疗老年女性骨质疏松性椎体压缩骨折临床研究[J].新中医,2020,52(10):26-29

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  • 在线发布日期: 2020-05-26
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