脐针联合健脾益胃汤治疗脾胃虚弱型慢性萎缩性胃炎临床研究
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Clinical Study on Navel Needling Combined with Jianpi Yiwei Tang for Chronic Atrophic Gastritis of Spleen-stomach Deficiency Type
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    摘要:

    目的:观察脐针联合健脾益胃汤治疗脾胃虚弱型慢性萎缩性胃炎(CAG) 的临床疗效。方法:选取72例脾胃虚弱型CAG 患者,按随机数字表法分为治疗组和对照组,每组36 例。对照组给予西药治疗,治疗组给予脐针联合健脾益胃汤治疗,1 个月为1 个疗程,2 组均连续治疗3 个疗程。治疗后对比2 组临床疗效,观察治疗前后临床症状积分、白细胞介素-8(IL-8)、C-反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α) 水平的变化。结果:治疗后,2组胃脘胀痛、胃痛及嗳气反酸积分均较治疗前下降(P<0.05);治疗组以上3项临床症状积分均低于对照组(P<0.05)。治疗组总有效率94.44%,高于对照组的80.56%(P<0.05)。治疗后,2组IL-8、CRP、TNF-α水平均较治疗前下降(P<0.05);治疗组IL-8、CRP、TNF-α水平均低于对照组(P<0.05)。结论:脐针联合健脾益胃汤治疗脾胃虚弱型CAG 疗效确切,较应用西药治疗能更好地改善患者的临床症状,降低IL-8、CRP、TNF-α水平。

    Abstract:

    Abstract:Objective:To observe the clinical effect of navel needling combined with Jianpi Yiwei tang for chronic atrophic gastritis(CAG) of spleen- stomach deficiency type. Methods: A total of 72 cases of CAG patients of spleen- stomach deficiency type were selected and divided into the treatment group and the control group according to the random number table method,36 cases in each group. The control group was treated with western medicine,and the treatment group was given navel needling combined with Jianpi Yiwei tang. One month being one course of treatment, both groups were continuously treated for three courses. After treatment,the clinical effect in the two groups was compared,and the changes of clinical symptom scores and levels of interleukin- 8(IL- 8),C- reactive protein(CRP) and tumor necrosis factor- α(TNF- α) before and after treatment were observed. Results: After treatment, the scores of epigastric distension and pain, stomachache, belching and acid regurgitation in the two groups were all decreased when compared with those before treatment(P<0.05);the above three clinical symptom scores in the treatment group was lower than that in the control group (P<0.05). The total effective rate was 94.44% in the treatment group,higher than that of 80.56% in the control group(P< 0.05). After treatment,the levels of IL-8,CRP and TNF-α in the two groups were all decreased when compared with those before treatment(P<0.05);the above levels in the treatment group were all lower than those in the control group(P<0.05). Conclusion: The therapy of navel needling therapy combined with Jianpi Yiwei tang has definite curative effect in treating CAG of spleen- stomach deficiency type. Compared with that of western medicine, it can better improve the clinical symptoms of patients and reduce the levels of IL-8,CRP and TNF-α.

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蒋毅玲,刘庆生.脐针联合健脾益胃汤治疗脾胃虚弱型慢性萎缩性胃炎临床研究[J].新中医,2020,52(8):142-144

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  • 在线发布日期: 2020-04-25
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