Abstract： Objective： To observe the clinical effect of coating with Qingpeng ointment combined with external application with borneol for phlebitis due to amiodarone. Methods： A total of 192 cases of patients with arrhythmia complicated with phlebitis due to micropump with amiodarone in our hospital were divided into the magnesium sulphate group(Group MS)，the Qingpeng ointment group(Group QP)，the borneol(Group BO) and the combination group(Group QP+ BO) according to the random number table method， 48 cases in each group. Group MS was given external application with 50% magnesium sulphate solution；Group QP was given local coating with Qingpeng ointment；Group BO was given local external application with sandbags with borneol；Group QP+BO was given coating with Qingpeng ointment combined with external application with borneol. All groups were treated for one week. On the 1st， 2nd， 3rd， 5th and 7th day of treatment respectively， the curative effect and the scores of pain of affected limbs were evaluated in the four groups. Results：On the 2nd，3rd，5th and 7th day of treatment，the total effective rates in the Group QP+BO were all higher than those in Group MS， Group QP and Group BO(P＜0.05). On the 1st， 2nd， 3rd， 5th and 7th day of treatment， there was no significant difference being found in the comparison of the total effective rate between Group QP and Group MS(P＞0.05). On the 1st and 2nd day of treatment，there was no significant difference being found in the comparison of the total effective rate between Group BO and Group MS(P＞0.05)；on the 3rd，5th and 7th day of treatment，the total effective rates in Group BO were lower than those in Group MS(P＜0.05). On the 1st，2nd，3rd，5th and 7th day of treatment，the scores of pain in Group QP+BO were all lower than those in Group MS，Group QP and Group BO respectively(P＜0.05). On the 1st，2nd，3rd，5th and 7th day of treatment，there was no significant difference being found in the comparison of the score of pain between Group QP and Group MS(P＞0.05). On the 2nd，3rd，5th and 7th day of treatment，the scores of pain in Group MS were lower than those in Group BO(P＜0.05). Conclusion： In the treatment of phlebitis due to amiodarone， the therapy of coating with Qingpeng ointment combined with external application with borneol has better curative effect than wet dressing with 50% magnesium sulphate solution.