Abstract：Objective：To observe the clinical effect of Xinbi tang combined with western medicine for chronic heart failure of coronary heart disease with qi-deficiency，blood-stasis and water-retention syndrome. Methods：A total of 100 cases of patients with chronic heart failure of coronary heart disease with qi-deficiency and blood-stasis syndrome were divided into the Chinese and western medicine therapy group and the western medicine group according to the random number table method，50 cases in each group. Both groups were treated with routine western medicine，and the Chinese and western medicine therapy group was additionally treated with Xinbi tang. Both groups were treated for four weeks. The clinical effect in the two groups was compared， the six- minute walking test was conducted before and after treatment， and the left ventricular ejection fraction(LVEF) was detected. Results：After treatment，the obvious effective rate for heart failure and the total effective rate in the Chinese and western medicine therapy group were higher than those in the western medicine group (P＜0.05). The total clinical effective rate in the Chinese and western medicine therapy group was higher than that in the western medicine group(P＜0.05). The six- minute walking distance and the values of LVEF in the Chinese and western medicine therapy group were longer or higher than those before treatment，differences being significant(P＜0.05)；the two indexes in the western medicine group were improved when compared with those before treatment， but there was no significance in the differenceP＞0.05)；the two indexes in the Chinese and western medicine therapy group were higher than those in the western medicine group，differences being significant(P＜0.05). Conclusion：The therapy of Xinbi tang combined with western medicine has significant effect in treating chronic heart failure of coronary heart disease with qi deficiency and blood stasis syndrome， which can effectively control the development of the disease and improve the heart function and sports ability of patients.