Objective：To observe the curative effect of modified Baihe tang combined with Zuojin pills for primary bile reflux gastritis.Methods：A total of 120 cases of patients with primary bile reflux gastritis were randomly divided into the observation group and the control group，60 cases in each group.The control group was treated with mosapride citrate tablets and hydrotalcite chewable tablets，and the observation group was additionally treated with modified Baihe tang combined with Zuojin pills based on the treatment of the control group.Both groups were treated for eight weeks.The clinical effect，the symptom scores and the bile reflux under gastroscope in the two groups were compared.Results：The total effective rate was 91.7% in the observation group，and 75.0% in the control group，the difference being significant(P＜ 0.05).After treatment，each symptom score in the observation group was improved when compared with that before treatment respectively(P ＜ 0.05)；except for the scores of dry mouth and bitter taste in mouth，each symptom score in the control group was improved when compared with that before treatment respectively(P＜ 0.05).After treatment，the comparison of symptom scores between the two groups showed significance in the difference(P＜0.05).The comparison of bile reflux under gastroscope before and after treatment in the observation group showed significance in the difference(Z=-9.564，P＜0.01).The comparison of bile reflux under gastroscope before and after treatment in the control group showed significance in the difference(Z=-9.560，P＜0.01).The comparison of bile reflux under gastroscope in the two groups showed significance in the difference(Z=-3.638，P ＜ 0.01).Conclusion：The therapy of modified Baihe tang combined with Zuojin pills can effectively treat primary bile reflux gastritis.