Abstract：Objective：To observe the effect of acupuncture and moxibustion and point application combined with special nursing on stroke patients with early microcirculation disturbance. Methods： A total of 56 cases of stroke patients were divided into the study group and the control group， 28 cases in each group. Both groups were given acupuncture and moxibustion and point application； the control group was given routine nursing； the study group was additionally given special nursing based on the treatment of the control group. After treatment，the changes in the scores of National Institutes of Health Stroke Scale(NIHSS) and modified Rankin Scale(mRS) were compared between the two groups. Results：Through intervention，the total effective rate was 71.42% in the control group and 89.28% in the study group，the difference being significant(P＜0.05). Through intervention， the scores of social participation， emotion， memory and thinking， and communication in the study group were all higher than those in the control group； when compared the scores of NIHSS between the two groups， the difference was significant(P＜0.05). Conclusion： The application of acupuncture and moxibustion and point application can effectively improve early microcirculation disturbance in stroke， but it needs special nursing measures as support. Based on the combination of treatment schemes， conditions of patients and their personal appeals，the nursing staffs should make a special nursing scheme and improve its application value.