Abstract：Objective：To observe the curative effect of Huoxue Xiaozhong tang combined with rehabilitation therapy on swelling，pain and wrist function of limbs in patients after operation for distal radius fracture. Methods：A total of 100 cases of patients with distal radius fracture，who were treated with locking compression plate(LCP) internal fixation，were selected and divided into the study group and the control group according to the random number table method， 50 cases in each group. After operation，the control group was given rehabilitation therapy，and the study group was additionally treated with Huoxue Xiaozhong tang based on the treatment of the control group. Both groups were treated for one month. The scores of symptoms and signs in the two groups were evaluated； the disappearance time of swelling， pain relief time and fracture healing time were recorded；the improvement of wrist function of patients was observed；the clinical effect was measured. Results：After treatment，the scores of symptoms and signs in the two groups were decreased when compared with those before treatment(P＜0.05)；the decrease of the above scores in the study group was more significant than that in the control group(P＜0.05). After treatment， in the study group， the disappearance time of swelling， pain relief time and fracture healing time were shorter than those in the control group(P＜0.05)；the scores of wrist function was lower than that in the control group(P＜0.05). The total effective rate was 96.00% in the study group and 74.00% in the control group， the difference being significant(P＜0.05). Conclusion： Huoxue Xiaozhong tang combined with rehabilitation therapy for patients after operation for distal radius fracture can relieve their limb swelling and pain，promote fracture healing and improve wrist function.