基于数据挖掘分析王会仍治疗肺结节用药规律
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R289;R563

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2018年度浙江省中医药科学研究基金项目(2018ZA039)


An Analysis of Administration Rule of WANG Huireng in Treating Pulmonary Nodules Based on the Data Mining
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    摘要:

    简版:目的:运用数据挖掘技术研究名老中医王会仍治疗肺结节的用药规律。方法:收集2叭8年1月1日 12月31日在浙江省中医院王会仍门诊诊治的肺结节患者病案资料,建立数据库,应用频数分析、关联规则分析、聚类分析进行数据挖掘。结果:共收集病例140诊次,涉及中药133味,累计用药频次2747次。其中补虚药、止咳化痰平喘药、清热药使用频率最高,分别占24.03%、20.28%、18.42%。获得高频药物40味,高频药物的药性以平、温、微寒为主,药味以甘、苦、辛为主。聚类分析显示高频药物可分为4类:疏肝解郁类、燥湿化痰类、补益脾肺类、清热散结类。……

    Abstract:

    Objective: To explore the administration rule of WANG Huireng, a famous veteran Chinese medicine practitioner,in treating pulmonary nodules based on the data mining.Methods:Patients with pulmonary nodules diagnosed and treated by WANG Huireng in the outpatient of Zhejiang Hospital of Chinese Medicine from January 1,2018 to December 31,2018 were collected.A database was established and the data mining technology was used to conduct frequency analysis,association rule analysis and cluster analysis.Results:A total of 140 cases were diagnosed,involving 133 kinds of Chinese herbal medicines,and the total frequency of medication was 2 747.Among them,the most frequently used herbal medicines were deficiency-tonifying medicine(24.03%),cough-relieving,phlegm-reducing and panting-relieving medicine(20.28%),and heat-clearing medicine(18.42%).Forty high-frequency medicines were obtained;their natures were mainly neutral,warm,and slightly-cold,and their flavors were mainly sweet,bitter and acrid.Cluster analysis showed that highfrequency medicines could be divided into four categories:liver-soothing and depression-relieving type,dampness-drying and phlegm-dissolving type,spleen-and-lung invigorating type,and heat-clearing and masses-dissipating type.The analysis of association rules showed that Semen Armeniacae Amarum-Bulbus Fritillariae Thunbergii and Rhizoma Fagopyri Dibotryis-Radix Apioris Fortunei were the core medicine pairs,and the core medicine combinations were Semen Armeniacae Amarum, Bulbus Fritillariae Thunbergii, Rhizoma Fagopyri Dibotryis, Radix Apioris Fortunei, Radix Ranunculi Ternati,Semen Coicis and Radix Pseudostellariae.Conclusion:WANG Huireng treats pulmonary nodules with both attention to reinforcing healthy qi and dispelling pathogenic factors, and specifically, reinforcing healthy qi as the main treatment complementary with dispelling pathogenic factors and with neutral medication.In addition to invigorating the spleen and lung,he also attaches importance to soothing the liver and relieving depression,nourishing the heart and calming the mind,and drying dampness and dissolving phlegm.

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罗旭平,王芳,陆盼盼,陈芳.基于数据挖掘分析王会仍治疗肺结节用药规律[J].新中医,2020,52(1):7-10

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  • 在线发布日期: 2020-01-06
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