To observe the clinical effect of KL-DB shortwave physiotherapy instrument combined with Qingre Liangxue tang for sensitive facial skin.Methods：Selected 40 cases of patients with sensitive facial skin，and divided them into the treatment group and the control group randomly，20 cases in each group.The treatment group received KL-DB shortwave physiotherapy instrument combined with Qingre Liangxue tang，while the control group only received Qingre Liangxue tang.The treatment of both groups lasted for 5 weeks.Before and after treatment，evaluated the clinical effect and safety，compared the status of transepidermal water loss(TEWL)in both groups，and recorded the occurrence of adverse reactions and its recurrence.Results：The physical signs in the treatment group were improved better than those in the control group，difference being significant(P ＜ 0.05).After treatment，TEWL in both groups was lower than that before treatment，differences being significant(P ＜ 0.05)；TEWL in the treatment group was decreased more significantly than that in the control group，difference being significant(P＜0.05).No severe adverse reactions occurred in both groups.Comparing with the recurrence rate in the two groups，there was no significant different being found(P ＞ 0.05).Conclusion：KL-DB shortwave physiotherapy instrument combined with Qingre Liangxue tang can safely and effectively treat sensitive facial skin，which is worthy of clinical promotion and application.