温肺散寒涤饮汤联合膀胱经姜疗法治疗慢性阻塞性肺疾病急性加重期临床研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R563.9

基金项目:

甘肃省中医药管理局科研计划项目(YB-20181492)


Clinical Study on Wenfei Sanhan Diyin Tang Combined with Ginger Therapy on the Bladder Meridian for Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:观察温肺散寒涤饮汤联合膀胱经姜疗法治疗外寒内饮证慢性阻塞性肺疾病急性加重期的临床疗效。方法:将140例患者随机分为实验组和对照组,每组70例;2组均采用氧疗支持、三联雾化吸入、止咳化痰、解痉平喘、纠正水电解质紊乱、抗生素等西医常规治疗,对照组加用膀胱经姜疗法治疗,实验组在对照组的基础上加用温肺散寒涤饮汤治疗,2组疗程均为2周;评估2组患者外寒内饮证候评分、BODE指数评分;检测2组患者肺功能指标[第一秒用力呼气容积(FEV1)、第一秒用力呼气容积所占百分比(FEV1%)、第一秒用力呼气容积占用力肺活量的百分比(FEV1/FVC%)]、血气指标[氧分压(PaO2)、二氧化碳分压(PaCO2)、血氧饱和度(SaO2)]、炎症指标[降钙素原(PCT)、白细胞介素-8(IL-8)、肿瘤坏因子-α(TNF-α)、血清淀粉样蛋白(SAA)]。结果:治疗后,2组患者BODE指数和外寒内饮证候评分均较治疗前降低(P<0.05),且实验组两项评分均低于对照组(P<0.05)。治疗后,2组患者血清PCT、IL-8、TNF-α、SAA均较治疗前降低(P<0.05),且实验组上述指标均低于对照组(P<0.05)。治疗后,2组患者肺功能指标FEV1、FEV1%、FEV1/FVC%均较治疗前升高(P<0.05),且实验组上述指标均高于对照组(P<0.05)。治疗后,2组患者PaO2、SaO2均较治疗前升高(P<0.05),PaCO2较治疗前降低(P<0.05);且实验组上述指标改善均优于对照组(P<0.05)。结论:温肺散寒涤饮汤联合膀胱经姜疗法治疗外寒内饮证慢性阻塞性肺疾病急性加重期患者,能显著改善患者肺功能和血气指标,降低血清炎症指标,从而促进病情康复。

    Abstract:

    To observe the clinical effect of Wenfei Sanhan Diyin tang combined with ginger therapy on the bladder meridian for acute exacerbation of chronic obstructive pulmonary disease of external cold with internal fluid retention type.Methods:A total of 140 cases of patients were randomly divided into the experiment group and the control group,70 cases in each group.Both groups were given routine western medicine treatments such as oxygen therapy,triple aerosol inhalation,suppressing cough and resolving phlegm,arresting convulsions and calming panting,correcting water-electrolyte imbalance and antibiotics; the control group was additionally treated with ginger therapy on the bladder meridian,and the experiment group was additionally treated Wenfei Sanhan Diyin tang based on the treatment of the control group.Both groups were treated for two weeks.The scores of external cold with internal fluid retention syndrome and the BODE indexes in the two groups were evaluated; the lung function indexes including forced expiratory volume in one second(FEV1), the percentage of predicted value of FEV1(FEV1%)and the ratio of forced expiratory volume in one second to forced vital capacity(FEV1/FVC%), the blood gas indexes including partial pressure of oxygen(PaO2), partial pressure of carbon dioxide(PaCO2)and oxygen saturation(SaO2),and inflammatory indexes including procalcitonin(PCT),interleukin-8(IL-8), tumor necrosis factor-α(TNF-α)and serum amyloid A(SAA)in the two groups were detected.Results:After treatment,the scores of BODE indexes and external cold with internal fluid retention syndrome in the two groups were decreased when compared with those before treatment(P < 0.05),and the above two scores in the experiment group were lower than those in the control group(P < 0.05).After treatment,the indexes of PCT,IL-8,TNF-α and SAA in serum in the two groups were decreased when compared with those before treatment(P < 0.05),and the above indexes in the experiment group were lower than those in the control group(P < 0.05).After treatment,the lung function indexes including FEV1,FEV1%and FEV1/FVC%in the two groups were increased when compared with those before treatment(P < 0.05),and the above indexes in the experiment group were higher than those in the control group(P < 0.05).After treatment,the indexes of PaO2and SaO2 in the two groups were increased when compared with those before treatment(P < 0.05),while the indexes of PaCO2were decreased when compared with those before treatment(P < 0.05);the improvement of the above indexes in the experiment group was superior to that in the control group(P<0.05).Conclusion:The therapy of Wenfei Sanhan Diyin tang combined with ginger therapy on the bladder meridian in treating acute exacerbation of chronic obstructive pulmonary disease of external cold with internal fluid retention type can significantly improve the lung function and the blood gas indexes and reduce the inflammatory indexes in serum,thereby promoteing the rehabilitation.

    参考文献
    相似文献
    引证文献
引用本文

屈蕾蕾,张衡中,杨瑞,徐莺,胡杰亮.温肺散寒涤饮汤联合膀胱经姜疗法治疗慢性阻塞性肺疾病急性加重期临床研究[J].新中医,2019,51(10):103-106

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2019-10-11
  • 出版日期: