血府逐瘀胶囊联合常规西药治疗心血瘀阻型冠心病心绞痛临床研究
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Clincial Study on Xuefu Zhuyu Capsules Combined with Routine Western Medicine for Angina Pectoris of Heart-blood Stasis Type
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    摘要:

    目的:观察血府逐瘀胶囊联合常规西药治疗心血瘀阻型冠心病心绞痛的临床疗效。方法:将105例心血瘀阻型冠心病心绞痛患者按随机数字表法分为研究组55例与对照组50例,对照组给予单纯西药治疗,研究组在对照组基础上给予血府逐瘀胶囊治疗,治疗后比较2组临床疗效、心绞痛情况、血液流变学情况。结果:研究组治疗后心绞痛临床总有效率为89.09%,高于对照组的70.00%,2组间比较,差异有统计学意义(P<0.05)。研究组心电图总有效率为85.45%,高于对照组的66.00%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组心绞痛发作次数、持续时间比较,差异无统计学意义(P>0.05);治疗后,2组心绞痛发作次数减少、持续时间缩短,研究组心绞痛发作次数低于对照组,持续时间短于对照组,2组比较,差异有统计学意义(P<0.05)。治疗前,2组全血黏度(高切、低切)、血浆黏度、纤维蛋白原及红细胞压积水平比较,差异无统计学意义(P>0.05)。治疗后,2组全血黏度(高切、低切)、血浆黏度、纤维蛋白原较治疗前降低,研究组各项指标水平低于对照组(P<0.05)。2组治疗前后红细胞压积水平比较,差异无统计学意义(P>0.05)。结论:对心血瘀阻型冠心病心绞痛患者采用血府逐瘀胶囊联合常规西药治疗,疗效确切,可缓解心绞痛。

    Abstract:

    To observe the clinical effect of Xuefu Zhuyu capsules combined with routine western medicine for angina pectoris of heart-blood stasis type.Methods:Divided 105 cases of patients with puerperal hypogalactia into two groups randomly,55 cases in the study group and 50 cases in the control group.The control group received simple western medicine,while the study group additionally received Xuefu Zhuyu capsules.After treatment,compared the clinical effect,the status of angina and hemorheology in both groups.Results:After treatment,the clinical total effective rate of angina was 89.09%in the study group,being higher than 70.00%in the control group,difference being significant(P< 0.05).The clinical total effective rate of electrocardiogram was 85.45%in the study group,being higher than 66.00%in the control group,difference being significant(P < 0.05).Before treatment,comparing the frequency of angina attacks and the duration in both groups,there was no significant difference being found(P > 0.05).After treatment,the frequency of angina attacks in both groups was reduced and the duration was shortened,and the frequency of angina attacks in the study group was lower than that in the control group and the duration was shorter than that in the control group,difference being significant(P<0.05).Before treatment,comparing the levels of whole blood viscosity(in high and low shear),plasma viscosity,fibrinogen and hematocrit in both groups,there was no significant difference being found(P > 0.05).After treatment,the levels of whole blood viscosity(in high and low shear),plasma viscosity and fibrinogen in both groups were lower than those before treatment,and each index above in the study group was lower than that in the control group(P < 0.05);comparing the level of hematocrit in both groups,there was no significant difference being found(P > 0.05).Conclusion:The application of Xuefu Zhuyu capsulescombined with routine western medicine hasexact therapeutic effect in treating angina pectorisof heart-blood stasis type,which can relieve angina.

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张海勋,侯凤芝,张强.血府逐瘀胶囊联合常规西药治疗心血瘀阻型冠心病心绞痛临床研究[J].新中医,2019,51(10):90-93

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  • 在线发布日期: 2019-10-11
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