Objective：To observe the curative effect of acupoint application of Chinese herbs for patients with liver cancer pain with syndrome of qi stagnation and blood stasis.Methods：Divided 102 cases of patients with primary liver cancer into two groups according to the random number table method，51 cases in each group.The two groups were adopted the“three-step analgesic ladder therapy” recommended in the Three-step Analgesic Ladder Guidelines for Cancer and treated with morphine sustained release tablets according to the initial condition.The control group received routine nursing measures，while the treatment group additionally received acupoint application of Chinese herbs based on the treatment of the control group.Both groups were observed continuously for four weeks.Compared scores of numerical rating scale(NRS)of pain，symptom scores of qi stagnation and blood stasis and clinical effect in the two groups，as well as recorded the occurrence of complications.Results：The total pain relief rate was 94.12%in the treatment group，higher than that of 78.43%in the control group(P＜0.05).After treatment，scores of NRS in the two groups were significantly reduced(P＜0.01).The score of NRS in the treatment group was lower than that in the control group after treatment(P＜0.01).After treatment，the symptom scores of qi stagnation and blood stasis in the two groups were significantly decreased(P＜0.01).The symptom score of qi stagnation and blood stasis in the treatment group was lower than that in the control group(P＜0.01).The complication rate was 3.92%in the treatment group，19.61%in the control group and significantly lower than that in the treatment group(P＜0.05).Conclusion：The therapy of routine western medicine and nursing combined with acupoint application of Chinese herbs for liver cancer pain，can obviously improve the cancer pain and clinical Chinese medicine symptoms of patients and improve clinical effect.