半夏泻心汤合旋复代赭汤加减治疗胃食管反流性咳嗽临床观察
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Clinical Observation of Modified Banxia Xiexin Tang Combined with Xuanfu Daizhe Tang for Gastroesophageal Reflux Cough
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    摘要:

    目的:观察半夏泻心汤合旋复代赭汤加减治疗胃食管反流性咳嗽(GERC)胃气上逆证的临床疗效。方法:将98例患者按随机数字表法分为2组各49例。对照组给予多潘立酮片及奥美拉唑肠溶片口服。观察组采用半夏泻心汤合旋复代赭汤加减。2组均治疗12周。进行治疗前后咳嗽症状评分及胃气上逆证评分。结果:经有序资料χ2检验,观察组临床疗效优于对照组,差异有统计学意义(χ2=5.571,P<0.05)。与治疗前比较,2组白天咳嗽评分、夜间咳嗽评分和总分均下降(P<0.01);与对照组比较,治疗后观察组白天咳嗽评分、夜间咳嗽评分和总分均低于对照组(P<0.01)。治疗后,2组咳嗽等症状评分均较治疗前下降(P<0.01),治疗后观察组除嗳腐吞酸、烧灼感外,其它各症状评分均低于对照组(P<0.01)。结论:半夏泻心汤合旋复代赭汤加减治疗GERC胃气上逆证能减轻咳嗽等症状,临床疗效优于西医治疗。

    Abstract:

    Objective:To observe the clinical effect of modified Banxia Xiexin tang combined with Xuanfu Daizhe tang for gastroesophageal reflux cough(GERC)with syndrome of adverse rising of stomach qi.Methods:Divided 98 cases of patients into two groups randomly according to random number table,49 cases in each group.The control group was given the oral administration of domperidone tablets and omeprazole enteric-coated tablets,while the observation group was given modified Banxia Xiexin tang combined with Xuanfu Daizhe tang.The treatment for both groups lasted for 12 weeks.Evaluated the scores of cough symptom and the syndrome of adverse rising of stomach qi before and after treatment.Results:According to ordinal data χ2test, the clinical effect of the observation group was better than that of the control group,difference being significant(χ2=5.571,P<0.05).Compared with those before treatment, the daytime cough scores,nighttime cough scores and the total scores in the two groups were all decreased(P<0.01).Compared with those in the control group,the daytime cough score,nighttime cough score and the total score in the observation group after treatment were all lower(P<0.01).After treatment,the scores of cough and other symptoms in the two groups were lower than those before treatment(P<0.01);except the scores of putrid belching and swallowing of up-cast gastric acid and burning sensation,other symptom scores in the observation group were all lower than those in the control group(P<0.01).Conclusion:The application of modified Banxia Xiexin tang combined with Xuanfu Daizhe tang for GERC with syndrome of adverse rising of stomach qi can reduce the cough and other symptoms.Its clinical effect is better than that of western medicine treatment.

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程茹.半夏泻心汤合旋复代赭汤加减治疗胃食管反流性咳嗽临床观察[J].新中医,2018,50(12):104-106

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  • 在线发布日期: 2018-12-09
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