Objective： To observe the clinical effect of qi-invigorating and blood-activating acupoint application for unstable angina pectoris in coronary heart disease of qi-deficiency and blood-stasis type.Methods：Included 60 cases of patients with unstable angina pectoris in coronary heart disease of qi-deficiency and blood-stasis type，and divided theminto the control group and the treatment group randomly，30 cases in each group.The control group was given the routine basic treatment，while the treatment group was additionally given qi-invigorating and blood-activating acupoint application.The course of treatment for both groups lasted for 2 weeks.Compared the clinical symptomscores of angina pectoris，Chinese medicine syndrome scores，and the clinical effect of angina pectoris and electrocardiogramin both groups before and after treatment.Results：After treatment，the clinical symptomscores of angina pectoris and Chinese medicine syndrome scores in both groups were lower than those before treatment( P ＜0.05)，and the clinical symptomscores of angina pectoris and Chinese medicine syndrome scores in treatment group were decreased more significantly than those in the control group( P ＜0.05).After treatment，the total obvious effective rate of the clinical effect of angina pectoris was 70.00%in the treatment group and 36.67%in the control group，difference being significant( P ＜0.05)；the total obvious effective rate of the clinical effect of electrocardiogram was 66.67%in the treatment group and 33.33%in the controlgroup，difference being significant( P ＜0.05).Conclusion：Qi-invigorating and blood-activating acupoint app lication is the effective method for treating unstable angina pectoris in coronary heart disease of qi-deficiency and blood-stasis type，which can relieve the clinical symptoms of unstable angina pectoris，decrease the pain degree of patients，and improve results in the electrocardiogram.