Objective： To study the clinical effect of Gexia Zhuyu tang com bined with precise transcatheter arterial chemoem bolization(TACE)for advanced prim ary liver cancer.Methods：Divided 60 cases of patients with prim ary liver cancer into the two groups，30 cases in each group.The control group received precise TACE for treatment，while the treatment group additionally received Gexia Zhuyu tang based on the treatment of the control group.Observed the changes of relevant indicators after treatment.Results：The volume of solid tumor in the two groups after treatment was decreased when compared with that before treatment( P ＜0.01)，but no significant difference was found in the comparison of the volume of solid tumor between the two groups( P ＞0.05).The effective rate of the solid tumor was 36.67%in the treatment group and was 26.67%in the controlgroup，there being no significance in the difference( P ＞ 0.05).After treatment，scores of Chinese medicine syndromes in the two groups were significantly improved when compared with those before treatment( P ＜0.01)，and the improvement in the treatment group was more obvious than that in the control group( P ＜0.01).After treatment，values of ALT， GGT， TBil and AFP in the two groups were significantly improved when compared with those before treatment( P ＜0.01)，and the improvement of values of ALT，GGT and AFP in the treatment group was more obvious than that in the control group( P ＜0.05， P ＜0.01).Conclusion：The therapy of Gexia Zhuyu tang com bined with precise TACE for prim ary liver cancer has accurate curative effect， which can obviously improve clinical symptoms of patients， the liver function and some biochemical indexes including AFP.