Objective： To observe the clinical effect of optimized XiaozhongKuiyongprescription for wound healing after operation for perianal abscess of toxic heat flourishing type.Methods：Divided 60 cases of patients of toxic heat flourishing type after operation for perianal abscess into the control group and the treatment group randomly，30 cases in each group.The control group was given routine sensitive antibiotics after operation by intravenous drip for three days，dressing change and self-m ade hemorrhoid washing formula tofumigate and wash the anus，while the treatment group was additionally given the oral administration of optimized XiaozhongKuiyong prescription.The treatment for both groups lasted for two courses，seven days per course.Compared the scores of visual analogue scale(VAS)and wound edem a on the 3 rd and 7 th day after operation as well as the wound exudation scores and wound healing time on the 3 rd ，7 th ，and 14 th day after operation in the two groups.Evaluated the clinical effect of two weeks of follow-up.Results：The scores of VAS and wound edem a in the treatment group on the 3 rd and 7 th day after operation were lower than those in the control group( P ＜0.05).The wound exudation scores on the 3 rd ，7 th and 14 th day after operation in the treatment group were lower than those in the controlgroup( P ＜0.05).The wound healing time in the treatment group was shorter than that in the control group( P ＜0.05).After two weeks of follow-up，the clinical effect in the treatment group was better than that in the control group，difference being significant( P ＜0.05).Conclusion：The application of XiaozhongKuiyong prescription can significantly reduce anal pain after operation for perianal abscess，wound edem a and wound exudation as well as other complications and shorten the wound healing time.It has a significant effect in treating wound healing after operation for perianal abscess of toxic heat flourishing type.