Objective：To discuss the theory basis，application range and clinical experience of du-moxibustion in treating chronic liver disease.The du-moxibustion is applicable to patients with syndromes of sthenic cold， asthenia-cold， qi stagnation，blood stasis and cold-dampness，which can also be applied in the treatment of patients with autoimmune liver disease，refractory jaundice，obstinate abdominal distension，depression and anxiety insomnia and low immunity.In those clinical experiences，the prime emphasis should be given to the application of du-moxibustion with syndrome differentiation，whose effect should be exerted in warming yang and dredging meridians，dispelling cold to relieve pain，and activating blood and dredging collaterals，and it should reinforce yin from yang in the treatment of yin deficiency syndrome.In addition，the application of moxibustion should be combined with oral administration of herbal medicine at the same time so as to complement each other and obtain a long-lasting clinical effect.