The advanced malignant tumors have a pathogenesis feature of Chinese medicine that is based on the theory of“zang-fu deficiency and yang-qi insufficiency”and characterized by“cancer poison”in the theory of“the accumulation of poison in the internal organs of the body does not flow” .“ Moxibustion therapy” is really consistent with the pathogenesis from its treatment methods to the choice of medicine, the amount, the selection of points and the rehabilitation measures,and it has achieved initial success in clinical applications,so that the authors shared it here.