Objective：To observe the effect of intelligent electroacupuncture combined with cognitive behavior intervention on self-efficacy of patients with schizophrenia.M e th o d s：Selected 108 cases of patients with schizophrenia hospitalized in our hospital， and divided them into two groups randomly， 54 cases in each group.Both groups received routine medicine combined with intelligent electroacupuncture for treatment.During treatment，the control group was given the routine intervention，including instructing patients on the drug using，enjoining them to follow the doctor's advice and emphasizing the importance of family care and psychological counseling to the family members of patients，while the observation group was given the cognitive behavior intervention.The treatment for both groups lasted for 3 months.Adopted the positive and negative syndrome scale(PANSS)，general self-efficacy scale(GSES)，Chinese medicine syndrome scale and schizophrenia quality of life scale(SQLS)to compare the clinical effect，self-efficacy and quality of life in both groups before and after treatment.Results：After treatment，the scores of positive symptoms，negative symptoms，general psychopathology and the total scores of PANSS in both groups were lower than those before treatment，and the observation group was lower than the control group，differences being significant(P ＜ 0.01，P ＜ 0.05).After treatment and 3 months after treatment，GSES scores in both groups were significantly higher than those before treatment，and the observation group was higher than the control group，differences being significant(P ＜ 0.01).After treatment and 3 months after treatment，scores of Chinese medicine syndrome scale in both groups were all lower than those before treatment，and the observation group was lower than the control group， differences being significant(P ＜ 0.01).After treatment， the scores of psychological society，motive/energy，symptoms/adverse rections and the total scores of SQLS in the observation group were respectively lower than those before treatment，and the observation group was lower than the control group，differences being significant(P ＜0.01).Conclusion：Intelligent electroacupuncture combined with cognitive behavior intervention can effectively release the clinical symptoms of patients with schizophrenia，promote their self-efficacy and improve their quality of life，which has a good clinical effect.