Objective：To discuss the clinical effect of self-made Shengbai tang combined with deep thermo therapy in preventing myelosuppression after chemotherapy.M e th o d s：Divided 73 cases of patients with malignant tumor into the treatment group being 37 cases and the control group being 36 cases randomly.The treatment group was given oral Shengbai tang combined with deep thermo therapy for treatment，while the control group was given leucogen tablets orally.After continuously treating for three weeks，detected the levels of total number of white blood cells(WBC)，hemoglobin(Hb)and changes of blood platelet count(BPC)before treatment and at the 1st，2ndand 3rdweek of treatment.Compared the clinical effect in two groups，and the improvement rate of quality of life in the two groups.Results：After one，two and three weeks of treatment，compared WBC in the two groups with those before treatment，differences being significant(P ＜ 0.05).After one and two weeks of treatment，there were no significant differences being found in WBC between the treatment group a n d the control group(P＜ 0.05).After three weeks of treatment，WBC in the treatment group was higher than that in the control group(P ＜ 0.05).After three weeks of treatment，there were no significant differences being found in the levels of Hb a n d BPC in the control group before and after treatment(P＞0.05).Levels of Hb and BPC in the treatment group were in creased when compared with those before treatment(P ＜ 0.05)，which were increased when compared with those in the control group(P ＜ 0.05).After treatment，the total effective rate was 91.9%in the treatment group and 69.4%in the control group，difference being significant(P＜0.05).The improvement rate of quality of life was 94.6%in the treatment group and 6 3.9% in the control group，difference being significant(P ＜ 0.05).Conclusion：The therapy of Shengbai tang combined with deep thermo therapy has an effect on improving myelosuppression after chemotherapy，can obviously increase the levels of WBC，Hb and BPC，and promote the clinical effect and improve quality of life.