Objective： To observe the clinical effect of point-application with Jiangzhi Faxia powder combined with tropisetron for nausea and vomiting caused by hematologic malignancies under chemotherapy.M e th o d s：Divided 206 cases of patients with hematologic malignancies into the test group being 115 cases and the control group being 91 cases randomly.The control group was given intravenous injection of tropisetron，routine nursing and placebo point-application，while the test group was additionally given point-application with Jiangzhi Faxia powder for treatment，once a day.The treatment lasted from the beginning of chemotherapy to its end(usually three to seven days).Compared the incidence of vomiting，degree of vomiting，incidence of nausea and degree of nausea of patients in the two groups after the start of chemotherapy for 12 h，1，2，3，4，5 and 6 days.Results：After the start of chemotherapy for12 h，1 and 2 days，the incidence of vomiting in the test group was lower than that in the control group(P ＜ 0.05)，while on 3，4，5，and 6 days of chemotherapy，there were no significant differences being found in the comparisons of incidence of vomiting between the test group and the control group(P＞0.05).During each period of time after the start of chemotherapy，the degree of vomiting in the test group was lower than that in the control group(P ＜ 0.05)，and the incidence of vomiting and degree of nausea in the test group were also lower than those in the control group(P＜0.05).Conclusion：The therapy of point-application with Jiangzhi Faxia powder combined with tropisetron can effectively relieve nausea and vomiting caused by chemotherapy in patients with hematological malignancies.