Objective:To observe the clinical effect of Hewei Huashi prescription for gastrointestinal dysfunction after gastrointestinal tumor operation and the effect on intestinal microecology of patients.Methods:Divided 100 cases of patients with gastrointestinal dysfunction after gastrointestinal tumor operation into the control group and the observation group randomly,50 cases in each group.The control group was given omeprazole enteric-coated capsules for treatment,while the observation group was given Hewei Huashi prescription for treatment.Recorded the improvement of each symptom,analyzed the treatment effect,and observed the changes of intestinal gram-negative and gram-positive bacteria.Results:The total effective rate was 98.00%in the observation group,being higher than that of 82.00%in the control group(P<0.05).After treatment,the scores of degree of abdominal pain,postprandial fulluess,early satiety and upper-abdominal burning in the two groups were all deceased when compared with those before treatment(P<0.05).The previous four symptom scores in the observation group were all lower than those in the control group(P < 0.05).After treatment,the gram-negative and gram-positive bacteria in the two groups reached the level of normal healthy people,and the improvements of the aforesaid intestinal flora in the observation group were significantly better than those of the control group,differences being significant(P < 0.05).Conclusion:The therapy of Hewei Huashi prescription has a significant effect in treating gastrointestinal dysfunction after gastrointestinal tumor operation,can evidently improve symptoms and signs of patients and regulate intestinal microecology.