Objective：To observe the clinical effect of integrated Chinese and western medicine therapy for allergic rhinitis and its safety.Methods：Divided 100 cases of patients with allergic rhinitis into the observation group and the control group randomly，50 cases in each group.The control group received the routine western medicine treatment，while the observation group additionally received Chinese herbal medicine Yuping Cang’er powder for treatment.Results：The total effective rate was 98.0%in the observation group and 78.0%in the control group，difference being significant(P＜0.05)；after treatment，comparing each symptom score of nasal obstruction，sneezing，rhinocnesmus and nasal discharge in both groups with those before treatment respectively，there were significant differences being found(P＜0.05)；comparing each symptom score of nasal obstruction，sneezing，rhinocnesmus and nasal discharge in the observation group with those in the control group，there were significant differences being found(P＜0.05).After treatment，the cured patients were followed up for 6 months，and the recurrence rate was 38.7%in the control group，being significantly higher than 11.6%in the observation group，difference being significant(P＜0.05).Conclusion：Integrated Chinese and western medicine therapy for allergic rhinitis has the definite clinical effect and high safety.