Objective：To observe the clinical effect of modified Danggui Buxue tang combined with routine treatment for uremic with anemia.Methods：Selected 60 cases of patients of uremic with anemia，and divided them into the observation group and the treatment group randomly，30 cases in each group.The observation group was given routine drug for treatment，while the treatment group was additionally given modified Danggui Buxue tang for treatment.Observed the changes of levels of hemoglobin(Hb)， hematocrit(HCT)， C-reactive protein(CRP)， interleukin-6(IL-6)， tumor necrosis factor-α (TNF-α)， serum K(K+)， and alanine aminotransferase(ALT)before and after treatment， and recorded the improvement of Chinese medicine symptoms of patients.Results：The total effective rate was 86.7%in the treatment group and was 56.7%in the control group，difference being significant(P＜0.05).After treatment，levels of Hb and HCT in two groups were both increased when compared with those before treatment(P＜0.05).The increase of those two indexes in the treatment group was more obvious than that in the control group(P＜0.05).Comparing with those before treatment，there were no significant changes being found in levels of CRP，IL-6 and TNF-α in the control group after treatment(P＜0.05)，while after treatment those three indexes in the treatment group were all decreased(P＜0.05).There were no significant effect being found in the comparisons of levels of K+and ALT in intra-group and inter-group comparison(P＜0.05).Conclusion：The therapy of modified Danggui Buxue tang combined with routine treatmentcan significantly increase levels of Hb and HCT in patients of uremic with anemia，reduce inflammation-relatedindex levels，and improve clinical symptoms，and its effect is better than the simple use of routine treatment.