Objective：To observe the clinical effect of Yiqi Wenyang Huayu prescription combined with western medicine for chronic congestive heart failure(CHF)in senile patients with yang-qi depletion accompanied with blood stasis syndrome.Methods：Divided 110 cases of patients admitted in our hospital into the control group and the treatment group randomly.The control group was given oral valsartan capsules，spironolactone tablets，carvedilol tablets，isosorbide mononitrate tablets and dioxin tablets for treatment，while the treatment group was additionally given Yiqi Wenyang Huayu prescription based on the treatment of the control group.The treatment of both groups lasted for six weeks.Evaluated Lee's heart failure score and scores of yang-qi depletion accompanied with blood stasis syndrome before and after treatment.Applied color doppler ultrasound testing system to determine values of left ventricular ejection fraction(LVEF)，cardiac output(CO)and the ratio value of peak systolic velocity in early diastolic phase by peak systolic velocity in late diastolic phase(E/A)，and conducted a walking test of six minutes.Assessed the quality of life by adopting minnesota living with heart failure questionnaire(MLHFQ)before and after treatment.Results：After treatment，the total effective rate was 94.55%in the treatment group，higher than that in the control group which was 81.82%，the difference being significant(P＜0.05).The Lee's heart failure scores，scores of yang-qi depletion accompanied with blood stasis syndrome in both groups and scores of MLHFQ in both groups were decreased when compared with those before treatment(P＜0.01).These three scores in the treatment group were lower than those in the control group(P＜0.01).Values of LVEF，CO，E/A and walking distance of six minutes in both groups were increased when compared with those before treatment(P＜0.01).These four indexes in the treatment group were higher than those in the control group(P＜0.01).Conclusion：The additional application of Yiqi Wenyang Huayu prescription based on the treatment of western medicine can effectively improve the symptoms，cardiac function and the quality of life in senile patients with CHF with yang-qi depletion accompanied with blood stasis syndrome.The clinical effect of this therapy is superior totreatment of simple western medicine.