Objective：To establish determination methods of the content of catechin，procyanidin B2，epicatechin and epicatechin gallate in peanut skin.Methods：Adopted the Kromasil C18chromatographic column(250×4.6 mm，5 μm).The mobile phase was acetonitrile-0.3%phosphoric acid with gradient elution.The flow velocity was 0.7 mL/min.The column temperature was 30℃.The injection volume was 10 μL.The detection wavelength was 278 nm.Results： The catechin，procyanidin B2， epicatechin and epicatechin gallate respectively had good linearity in the ranges of 0.155 ～1.162 μg，0.156～1.168 μg，0.161～1.204 μg and 0.151～1.128 μg.The regression equation respectively was Y=5.367×105X+1.231×104，r=0.999 7；Y=5.639×105X+1.475×104，r=0.999 5；Y=6.151×105X+4.007×103，r=0.999 6；Y=4.874×105X+3.277×104，r=0.999 6.The average recovery respectively was 98.3%(RSD=1.2%)，97.6%(RSD=1.7%)，98.0%(RSD=1.0%)，and 98.2%(RSD=1.3%).Conclusion：The method established in the study is simple，efficient and rapid with high accuracy and good reproducibility，which can be used for the quality control of peanut skin.