Objective: To observe the relationship between the clinical effect of Qiyu Sanlong tang on patients with non-small cell lung cancer(NSCLC)in moderate and advanced stages and Chinese medicine syndrome types.Methods:Selected 31 cases of patients with NSCLC and gave them oral administration of Qiyu Sanlong tang and symptomatic treatment based on the routine treatment.Observed the clinical effect,scores of quality of life,improvement of clinical symptoms,median survival time,disease-free progressive stage and one-year survival rate of patients after treatment.Applied the assessment scale of quality of life(FACT-L)to collect,organize and record the information on quality of life of patients into the database.Results: In patients with NSCLC in moderate and advanced stages, yin-deficiency and heat-toxin type,qi-deficiency and phlegm-dampness type were of the majority among Chinese medicine syndrome types.With the prolongation of disease course in patients,the proportion of the qi-yin deficiency type was constantly increased,and Qiyu Sanlong tang made higher curative effective rate and quality of life on the qi-yin deficiency type,which had advantages.The higher scores of Karnofsky performed,the better the clinical effect patients had.After treatment,the clinical symptoms of patients were significantly improved, and the survival time was prolonged, which were positively correlated with the intervention time of Qiyu Sanlong tang.Conclusion:Qiyu Sanlong tang has certain effect on the tumor stability of NSCLC in moderate and advanced stages,and has certain improvement on the quality of life of patients.