Objective： To observe the clinical effect of Dan'e Fukang decocted extract combined with mifepristone capsules for endometriosis and its effect on serum endometrium antibody(EmAb)of patients.Methods：Selected 112 cases of patients with endometriosis as study subjects，and divided them into the study group and the control group randomly，56 cases in each group.The control group was given mifepristone capsules for treatment，while the study group was given Dan'e Fukang decocted extract combined with mifepristone capsules for treatment.Evaluated the curative effect of both groups， detected the positive rate of serum EmAb in patients before and after treatment， and compiled statistics of pregnancy.Results：The total effective rate was 91.07% in the study group and was 75.00% in the control group，the difference being significant(P ＜ 0.05).Before treatment，there was no significant difference being found in the comparison of positive rate of serum EmAb in the two groups(P ＞ 0.05).After treatment，the positive rate of serum EmAb in the two groups were decreased when compared with those before treatment，differences being significant(P ＜ 0.01).The positive rate of serum EmAb in the study group were lower than those in the control group，the difference being significant(P＜0.05).After treatment，there were 12 cases of pregnancy in the study group，pregnancy rate being 21.43%.There were 4 cases of pregnancy in the control group，pregnancy rate being 7.14%.Compared the pregnancy rate of both groups，there was significance in the difference(P＜ 0.05).Conclusion：The therapy of Dan'e Fukang decocted extract combined with mifepristone capsules for endometriosis can improve the curative effect.